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O2(C1(=C(C(OC)=CC=C1C3(=C2C=CC=C3))CN4(CCCC4)))

Molecule Name:	39322
Refractivity:	83.77
Resonant Structures:	200
topological PSA:	25.61
ASA hydrophobic:	474.03
ASA polar:	24.27
Accessible Surface Area:	498.30
cLogS:	-4.494
MW:	281.354
cLogP:	3.772
H-Acceptors:	3
H-Donors:	0
Ro5 violations:	0
DrugScore:	0.662826112
Druglikeness:	2.2622
Irritant:	none
Mutagenic:	none
Reproductive Effective:	none
Tumorigenic:	none
Fish Toxicity:	High FHMT
Fish Toxicity2:	0.826
Rat Acute Toxicity:	3.2394
Acute Oral Toxicity:	II
Caco-2 Permeability:	Caco2+
Caco-2 Permeability2:	1.3172
P-glycoprotein Inhibitor2:	Substrate
P-glycoprotein Inhibitor:	Inhibitor
P-glycoprotein Inhibitor2:	Inhibitor
Human Ether-a-go-go-Related Gene Inhibition:	Strong inhibitor
Human Ether-a-go-go-Related Gene Inhibition2:	Inhibitor
CYP450 2C9 Substrate:	Non-substrate
Tetrahymena Pyriformis Toxicity :	High TPT
Tetrahymena Pyriformis Toxicity2:	0.3017
AMES Toxicity:	AMES toxic
CYP450 3A4 Inhibitor:	Substrate
CYP450 3A4 Substrate:	Non-inhibitor
CYP450 2C19 Inhibitor:	Non-inhibitor
CYP450 2C9 Inhibitor:	Non-inhibitor
CYP450 2D6 Inhibitor:	Inhibitor
CYP450 1A2 Inhibitor:	Inhibitor
CYP450 2D6 Substrate:	Substrate
Biodegradation:	Not ready biodegradable
Carcinogens:	Non-carcinogens
Blood-Brain Barrier:	BBB+
CYP Inhibitory Promiscuity:	High CYP Inhibitory Promiscuity
Honey Bee Toxicity:	Low HBT
Renal Organic Cation Transporter:	Inhibitor
Carcinogenicity (Three-class):	Non-required
Human Intestinal Absorption:	HIA+

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